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HAEMATOLOGICAL VALUES OF VESICO VAGINAL FISTULA PATIENTS AND THE MOST PREVALENT PATHOGENS

Thesis, Project Topic: Haematological Values of Vesico Vaginal Fistula (VVF) Patients in National Obstetric Fistula Centre, Abakaliki, and the Most Prevalent Pathogens in their Urine and High Vaginal Swab


ABSTRACT

 Vesico Vaginal fistula (VVF) is a subtype of Female urogenital fistula (UGF). It is an abnormally fistulous tract extending between the bladder and the vagina that allows the continuous involuntary discharge of urine into the vaginal vault. In addition to sequelae from this fistula, it has a profound effect on the patients emotional well being.  This study investigated some haematological parameters in Vesico Vaginal Fistula patients and the most prevalent pathogens in their urine and high vaginal swab. The haematological parameters and microbial isolations were analysed in 85 samples (55 tests and 30 controls) of patients and apparently healthy individuals within the age bracket of 15-50 years and haematological parameter analyses in the test included: PCV, WBC, HB, Retics, platelets and differential. This evaluation was carried out in pre – op stage (before surgery) of the VVF patients. The following mean values were obtained: WBC (control = 6.1±0.9, test = 6.0±0.9), Platelets (control = 263 ± 64, test = 254 ± 80), Retics (control =1.6±0.13, test = 1.4±0.24), Lymphocytes (control = 40.6±7.4, test = 41.2±9.7), monocytes (control = 7.0±2.9, test = 8.0±3.8) were all insignificant, while PCV (control = 39.0± 3.7, test = 32.0±5.4), Hb (control = 13.0±4.0, test = 11.0±1.9), Neutrophil (control = 54.0±7.7, test = 48.0±10.6), Eosinophil (control = 3.1±0.1, test = 4.4±4.4) were significant. As for the isolation of the pathogens, the following microorganisms were isolated in the following order of prevalence in percentages namely: Escherichia coli (54%), Klebsiella (13%), Pseudomonas (4%) and Proteus  (25%) which were all gram negative. Since the result suggests more insignificance than significant values, therefore it can be inferred that vesico vaginal fistula has less significant effect on haematological parameters especially when infection is minimal or absent.

CHAPTER ONE

1.0                                     INTRODUCTION

1.1.   OVERVIEW

Vesico Vaginal Fistula (VVF) is a devastating childbirth injury that results in the abnormal fusion between the urinary bladder and the vagina. VVF is the most common kind of gynecological abnormality (fistula) in the developing countries, Andrew (1999) described it as an old menace to mankind and a constant source of misery to the affected patient. Latest estimates suggest that 3 million women live with fistula, they are found in mainly South Asia and sub-Saharan Africa (Wall 2006).

1.2 DEFINITION

Vesico vaginal fistula (VVF) is a subtype of female Urogenital fistula (UGF). VVF is an abnormal fistulous tract extending between the bladder and the vagina that allows the continuous involuntary discharge of urine into the vaginal vault. Adding to the medical sequelae from these fistulas they often have a deep effect on the patient’s emotional well-being (Ingelman et al., 2009).

A VVF is an abnormal communication between the urinary bladder and the vagina that results in the continuous involuntary discharge of urine into the vaginal vault. Before consideration for a repair accurate diagnosis is paramount. Various methods are available to the clinician and any extreme or suspicious vaginal discharge in a patient who recently underwent pelvic surgery or who has a history of pelvic radiotherapy should be evaluated without delay for a urogenital fistula (UGF) (Jobert  et al., 1852).

1.3 AIM AND OBJECTIVE OF THE STUDY

The aim of this project was to investigate some haematological values of patients suffering from vesico vaginal fistula and the most prevalent pathogens in their urine and high vaginal swab samples, at National Obstetric Fistula Centre, Abakaliki.

This research has the following objectives:

1.       To obtain, evaluate and analyse some haematological values of       patients suffering from vesico vaginal fistula (VVF) and

2.       To isolate the most prevalent pathogens in their high vaginal swabs         (HVS) and urine samples.

1.4 JUSTIFICATION

These patients are prone to chronic infection. It is therefore necessary to take adequate precaution to avoid complications in an already poor condition.

—This article is incomplete———–This article is incomplete———— It was extracted from a well articulated quality Project, Research Work/Material

Topic: Thesis, Project Topic: Haematological Values of Vesico Vaginal Fistula Patients in National Obstetric Fistula Centre, Abakaliki, and the Most Prevalent Pathogens in their Urine and High Vaginal Swab

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